LEADER 04668cam a2200289 a 4500
001 1128975
008 220923s2021 nyua g b 001 0deng d
010 $a2020043552
020 $a9781982115852$q(hbk.) :$cUSD35.00
020 $a1982115858$q(hbk.) :$cUSD35.00
035 $aNO000222231
037 $b公共圖書館臺南分區資源中心
040 $aDLC$beng$eaacr2$cDLC$dOCLCO$dOCLCF$dORX$dSINLB$dFNN$dOI6$dYDX$dJPL$dTCH$dILC$dDLC$dBKL$dVP@$dIMD$dOTP$dOCLCO$dUND$dYUS$dAOW$dJYJ$dGYG$dERASA$dWVU$dTWTNM
041 0 $aeng
042 $apcc
050 00$aQH440$b.I83 2021
082 00$a576.5$223
090 $a臺南市立圖書館
100 1 $aIsaacson, Walter.
245 14$aThe code breaker :$bJennifer Doudna, gene editing, and the future of the human race /$cWalter Isaacson.
246 30$aJennifer Doudna, gene editing, and the future of the human race
250 $a1st Simon & Schuster hardcover ed.
260 $aNew York, NY :$bSimon & Schuster,$cc2021.
300 $axix, 536 p. :$bill. (chiefly col.) ;$c24 cm.
504 $aIncludes bibliographical references and index.
505 00$gIntroduction.$tInto the breach --$gPart one.$tThe origins of life.$tHilo ;$tThe gene ;$tDNA ;$tThe education of a biochemist ;$tThe human genome ;$tRNA ;$tTwists and folds ;$tBerkeley --$gPart two.$tCRISPR.$tClustered repeats ;$tThe Free Speech Movement Café ;$tJumping in ;$tThe yogurt makers ;$tGenentech ;$tThe lab ;$tCaribou ;$tEmmanuelle Charpentier ;$tCRISPR-Cas9 ;$tScience, 2012 ;$tDueling presentations --$gPart three.$tGene editing.$tA human tool ;$tThe race ;$tFeng Zhang ;$tGeorge Church ;$tZhang tackles CRISPR ;$tDoudna joins the race ;$tPhoto finish ;$tDoudna's final sprint ;$tForming companies ;$tMon amie ;$tThe heroes of CRISPR ;$tPatents --$gPart four.$tCRISPR in action.$tTherapies ;$tBiohacking ;$tDARPA and anti-CRISPR --$gPart five.$tPublic scientist.$tRules of the road ; t Doudna steps in --$gPart six.$tCRISPR babies.$tHe Jiankui ;$tThe Hong Kong summit ;$tAcceptance --$gPart seven.$tMoral questions.$tRed lines ;$tThought experiments ;$tWho should decide? ;$tDoudna's ethical journey --$gPart eight.$tDispatches from the front.$tQuebec ;$tI learn to edit ;$tWatson revisited ;$tDoudna pays a visit --$gPart nine.$tCoronavirus.$tCall to arms ;$tTesting ;$tThe Berkeley lab ;$tMammoth and Sherlock ;$tCoronavirus tests ;$tVaccines ;$tCRISPR cures ;$tCold Spring Harbor virtual ;$tThe Nobel Prize.
520 $aThe bestselling author of Leonardo Da Vinci and Steve Jobs returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback, titled The Double Helix, on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the building blocks of life. Even though her high school counselor told her girls didn't become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book's author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned their curiosity into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for COVID-19 will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution: children who study digital coding will be joined by those who study the code of life. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful book that would be! And what about preventing depression? Hmm...should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Novel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species. --$cFrom dust jacket.
600 10$aDoudna, Jennifer A
650 0$aCRISPR (Genetics).
650 0$aGene editing.
653 $a知識性
653 $a科技創新